Publications — Elia Lab

Selected Publications

Moore CE, Yalcindag SE, Czeladko H, Ravindranathan R, Wijesekara Hanthi Y, Levy JC, Sannino V, Schindler D, Ciccia A, Costanzo V, Elia AE.* (2023) RFWD3 Promotes ZRANB3 Recruitment to Regulate the Remodeling of Stalled Replication Forks. J Cell Biol, 2023 May 1; 222(5):e202106022, Link to PDF.

Adeyemi RO, Willis NA, Elia AE, Clairmont C, Li S, Wu X, D’Andrea AD, Scully R, and Elledge SJ. (2021) The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair. Molecular Cell 81(21):4440-56

Duan H, Mansour S, Reed R, Gillis MK, Parent B, Liu B, Sztupinszki Z, Birkbak N, Szallasi Z, Elia AE, Garber JE, Pathania S. (2020) E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells. J Cell Biol 219(6):e201908192

Reitman ZJ, Winkler F, Elia AE. New Directions in the Treatment of Glioblastoma. Seminars in Neurology. 2018; 38(1):50-61.

Zhou C*, Elia AE*, Naylor ML, Dephoure N, Ballif BA, Goel G, Xu Q, Ng A, Chou DM, Xavier RJ, Gygi SP, Elledge SJ. (2016) Profiling DNA damage-induced phosphorylation in budding yeast reveals diverse signaling networks. Proc Natl Acad Sci U S A. 113(26):E3667-75 (*co-first)

Elia AE, Wang DC, Willis NA, Boardman AP, Hajdu I, Adeyemi RO, Lowry E, Gygi SP, Scully R, Elledge SJ. (2015) RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks. Molecular Cell. 60(2):280-93.

Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ. (2015) Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response. Molecular Cell. 59(5):867-81.

Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ. (2011) Global identification of modular cullin-RING ligase substrates. Cell. 147(2):459-74.

Elia AE, Cantley LC, Yaffe MB. (2003) Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates . Science. 299:1228-31.

Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB. (2003) The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell. 115:83-95.

Publications

Reitman ZJ, Winkler F, Elia AE. New Directions in the Treatment of Glioblastoma. Seminars in Neurology. 2018; 38(1):50-61.

Wick A, Kessler T, Elia AE, Winkler F, Batchelor TT, Platten M, Wick W.. (2018) Glioblastoma in the elderly: solid conclusions built on shifting sand? Neuro-Oncology 20(2):174-183.

Willis NA, Zhou C, Elia AE, Murray JM, Carr AM, Elledge SJ, Rhind N. (2016) Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks. Proc Natl Acad Sci U S A 113(26):E3676-85

Gao J, Kim HM, Elia AE, Elledge SJ, Colaiácovo MP. (2015) NatB Domain-Containing CRA-1 Antagonizes Hydrolase ACER-1 Linking Acetyl-CoA Metabolism to the Initiation of Recombination during C. elegans Meiosis. PLoS Genet 11(3):e1005029

Pavlova NN, Pallasch C, Elia AE, Braun CJ, Westbrook TF, Hemann M, Elledge SJ. (2013) A role for PVRL4-driven cell-cell interactions in tumorigenesis. Elife e00358

John SP, Chin CR, Perreira JM, Feeley EM, Aker AM, Savidis G, Smith SE, Elia AE, Everitt AR, Vora M, Pertel T, Elledge SJ, Kellam P, Brass AL. (2013) The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication. J Virol. 87(14): 7837-52.

Wang CI, Alekseyenko AA, LeRoy G, Elia AE, Gorchakov AA, Britton L-MP, Elledge SJ, Kharchenko PV, Garcia BA, Kuroda MI. (2013) Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Nat Struct Mol Biol. 20(2): 202-9.

Elia AE, Elledge SJ. (2012) BRCA1 as tumor suppressor: lord without its RING? Breast Cancer Res. 14:306.

Emanuele MJ, Ciccia A, Elia AE, Elledge SJ. (2011) Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate. Proc Natl Acad Sci U S A. 108(24):9845-50.

Elia AE, Shih HA, Loeffler JS. (2007) Stereotactic Radiation for Meningiomas. Neurosurgery Focus 23(4): E5

Benes CH, Wu N, Elia AE, Dharia T, Cantley LC, Soltoff SP. (2005) The C2 domain of PKCdelta is a phosphotyrosine binding domain. Cell 121:271-80.

Mah AS, Elia AE, Devgan G, Ptacek J, Schutkowski M, Snyder M, Yaffe MB, Deshaies RJ. (2005) Substrate specificity analysis of protein kinase complex Dbf2-Mob1 by peptide library and proteome array screening. BMC Biochem. 6:22.

Manke IA, Nguyen A, Lim D, Stewart MQ, Elia AE, Yaffe MB. (2005) MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation. Molecular Cell 17:37-48.

Elia AE, Yaffe MB. (2004) Phosphoserine/threonine binding domains. In Modular Protein Domains Edited by G. Cesareni, et al. Wiley-Vch Verlag GmbH & Co., Weinheim. 163-179.

Lowery DW, Mohammad DH, Elia AE, Yaffe MB. (2004) The Polo-box domain: a molecular integrator of mitotic kinase cascades and Polo-like kinase function. Cell Cycle 3:128-31.

Elia AE, Cantley LC, Yaffe MB. (2003) Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates . Science. 299:1228-31.

Brown GE, Stewart MQ, Bissonnette SA, Elia AE, Wilker E, Yaffe MB. (2003) Distinct ligand-dependent roles for p38 MAPK in priming and activation of the neutrophil NADPH oxidase. J Biol Chem. 279:27059-68.

Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AE, Lu W, Brown EM, Quinn SJ, Ingber DE, Zhou J. (2003) Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nature Genetics 33:129-37.

Yaffe MB, Elia AE. (2001) Phosphoserine/threonine-binding domains. Curr Opin Cell Biol. 13:131-8.

Liu X, Elia AE, Law SF, Golemis EA, Farley J, Wang T. (2000) A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1. EMBO J. 19:6759-69.